Radiation therapy of seminoma of the testis

Journal Article · Mon Jun 01 00:00:00 EDT 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(81)90463-6· OSTI ID:6341635

Tu-nan, Q; Yu-hua, H; Chih-xian, C; Yu-qin, Q; Da-zhong, G; Xian-zhi, G

Seventy-three consecutive patients with seminoma of the testis were treated by orchiectomy followed by radiation alone. Sixty-six patients (91%) survived for more than five years. Forty-nine of fifty-six (87%) survived for more than ten years. The five-year survival for 54 patients with Stage I disease was 100%; it was 92% for 13 patients with Stage II disease. None of the six Stage III patients survived. All those who survived for five years were leading an active and normal life as of this writing. The Karnofsky's performance status was 90 to 100 for 50 patients who were followed in detail. Routine postoperative irradiation of the para-aortic lymphatics was sufficient to produce a permanent cure without resorting to chemotherapy or prophylactic irradiation of mediastinum and supraclavicular regions. The optimal tissue dose was 3000 rad. It may be increased to 3500 to 4000 rad by reducing the portal, but the total dose should be kept under 4000 rad. Pulmonary metastases were treated by bilateral whole lung irradiation of 1000 to 1500 rad followed by a local boost dose of 2000 to 2500 rad. The treatment was well-tolerated by the patient. Large intra-abdominal metastases involving the internal organs should be treated by means other than radiation alone.

• Research Organization: Chinese Academy of Medical Sciences, Beijing
• OSTI ID: 6341635
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 7:6
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
CARCINOMAS
BIOLOGICAL RADIATION EFFECTS
TESTES
COBALT 60
DOSE-RESPONSE RELATIONSHIPS
EXTERNAL IRRADIATION
METASTASES
PATIENTS
RADIATION DOSES
RADIOTHERAPY
SURGERY
SURVIVAL TIME
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
COBALT ISOTOPES
DISEASES
DOSES
GONADS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MALE GENITALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
THERAPY
YEARS LIVING RADIOISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)
551001 - Physiological Systems- Tracer Techniques