Radioactive colloidal gold in the treatment of endometrial cancer: Mayo Clinic experience, 1952 to 1976
- Mayo Clinic, Rochester, MN
A review of 1670 patients with endometrial cancer who were treated between 1952 and 1976 revealed that 15 patients had received radioactive colloidal gold as an adjunct to surgery. Most of the patients had follow-up of more than ten years, and all had microscopic tumor contamination of the peritoneal cavity. Of the 15 patients, 13 had biopsy of peritoneal metastases and underwent resection of gross metastatic lesions that were more than 2 mm in diameter. The other two patients had direct extension of the tumor through the uterus into the peritoneal cavity without visible metastasis. The radiogold was inserted from 4 to 37 days after the initial surgical procedure. The dosage ranged from 100 to 140 mCi. At follow-up, from 11 years seven months to 24 years two months after treatment, seven patients were alive without evidence of disease. Three died of intercurrent disease, 16, 14 years, and 14 years two months after treatment. Five patients died of cancer, two with local recurrence and three with distant metastases to lung or bone (or both).
- OSTI ID:
- 6337182
- Journal Information:
- Cancer; (United States), Vol. 47:10; Conference: meeting of the American Radium Society, Philadelphia, PA, 27 April 1980
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
PATHOLOGICAL CHANGES
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
SMALL INTESTINE
DELAYED RADIATION EFFECTS
GOLD 198
METASTASES
NEOPLASMS
PATIENTS
RADIATION SOURCE IMPLANTS
RADIOCOLLOIDS
RADIUM
SURGERY
UTERUS
ALKALINE EARTH METALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
COLLOIDS
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
ELEMENTS
FEMALE GENITALS
GASTROINTESTINAL TRACT
GOLD ISOTOPES
HEAVY NUCLEI
IMPLANTS
INTESTINES
ISOTOPES
MEDICINE
METALS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATION EFFECTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
THERAPY
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)