Postoperative irradiation in carcinoma of the prostate

Conference · Mon Oct 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

OSTI ID:6302474

Pilepich, M V; Walz, B J; Baglan, R J

Twenty-eight patients received postoperative radiotherapy with curative intent following either radical prostatectomy (18 patients) or enucleative prostatectomy (10 patients). In patients undergoing radical prostatectomy, the indications for postoperative radiotherapy included positive margins in 13, close margins in 2, and seminal vesicle involvement in 3 patients. The majority of patients (82%) received total dose to the prostatic bed in excess of 6500 rad. In over 80% of the patients, the pelvic lymphatics are also treated (to a total dose of 4000-5000 rad). All of the patients irradiated after radical prostatectomy clinically remained disease-free locally. Approximately one-half of the patients in both the enucleation and radial prostatectomy groups developed evidence of distant metastases. The complications of treatment have been comparable to those in patients treated with radiotherapy only. The continence status has not been affected significantly. All patients with incontinence following completion of radiotherapy had documented impairment of continence prior to radiotherapy. Postoperative radiotherapy administered following either radical or enucleative prostatectomy was tolerated well and resulted in excellent local control.

• Research Organization: Washington Univ. School of Medicine, St. Louis, MO
• OSTI ID: 6302474
• Report Number(s): CONF-8310342-; TRN: 85-001043
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:10; Conference: 25. annual meeting of the American Society of Therapeutic Radiologists, Los Angeles, CA, USA, 3 Oct 1983
• Country of Publication: United States
• Language: English

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