Dimethylnitrosamine demethylase activity in Drosophila melanogaster
Journal Article
·
· Biochem. Biophys. Res. Commun.; (United States)
A dimethylnitrosamine (DMN) demethylase with levels of activity comparable to that in uninduced rat liver was demonstrated in both larval and adult forms of the Hikone-R strain of Drosophila. A microsomal enzyme, it has many properties of a cytochrome P-450-containing mixed-function oxidase. Kinetic analysis indicates only a single enzyme with an apparent K/sub m/ of 10.5 mM DMN.
- DOE Contract Number:
- W-7405-ENG-26
- OSTI ID:
- 6299945
- Journal Information:
- Biochem. Biophys. Res. Commun.; (United States), Vol. 106:3
- Country of Publication:
- United States
- Language:
- English
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Dimethylnitrosamine demethylase activity in Drosophila melanogaster
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+1 more
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
DROSOPHILA
ENZYME ACTIVITY
BIOCHEMICAL REACTION KINETICS
ENZYMES
METHYL RADICALS
MICROSOMES
NITROSAMINES
ALKYL RADICALS
AMINES
ANIMALS
ARTHROPODS
CELL CONSTITUENTS
DIPTERA
FLIES
FRUIT FLIES
INSECTS
INVERTEBRATES
KINETICS
NITROSO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOIDS
RADICALS
REACTION KINETICS
550200* - Biochemistry
DROSOPHILA
ENZYME ACTIVITY
BIOCHEMICAL REACTION KINETICS
ENZYMES
METHYL RADICALS
MICROSOMES
NITROSAMINES
ALKYL RADICALS
AMINES
ANIMALS
ARTHROPODS
CELL CONSTITUENTS
DIPTERA
FLIES
FRUIT FLIES
INSECTS
INVERTEBRATES
KINETICS
NITROSO COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOIDS
RADICALS
REACTION KINETICS
550200* - Biochemistry