Relative flow of blood cells, platelets, and microspheres in outer and inner renal cortex
Blood platelets (Pl) may attain a relatively high marginal concentration in arterioles, perhaps also in arteries. Along a renal interlobular artery, blood passes several successive arterioles, each arteriole receiving a small flow fraction from a narrow zone adjacent to the artery wall. Thus, in theory, the Pl concentration should cumulatively decrease as the blood approaches the outer cortex, contrary to the concentration of red and white blood cells (RBC and WBC). This was tested by assessing the concentrations of these blood elements, and for comparison, the concentrations of 0.3-, 1.8-, and 3.5- m microspheres (MS), in serial blood samples from veins separately draining the outer and inner cortex in cat kidney. The outer-to-inner cortical concentration ratio was 1.28 for WBC, 1.04 for RBC, and 0.75 for Pl, confirming the working hypothesis. The RBC demargination corresponded to that of MS smaller that 1.8 m, the demargination of WBC to that of MS larger than 3.5 m. In contrast to Pl the even smaller 0.3- m MS were not marginated. Thus, the margination of platelets may not be due merely to their small size.
- Research Organization:
- Univ. of Bergen, Norway
- OSTI ID:
- 6292050
- Journal Information:
- Am. J. Physiol.; (United States), Vol. 251:2
- Country of Publication:
- United States
- Language:
- English
Similar Records
Countercurrent diffusion in the renal cortex of the rabbit
Angiotensin II receptors in rabbit renal preglomerular vessels
Related Subjects
BLOOD CELLS
BLOOD FLOW
BLOOD PLATELETS
KIDNEYS
DYNAMIC FUNCTION STUDIES
PHYSIOLOGY
MICROSPHERES
BLOOD PRESSURE
CATS
IODINE 125
STRONTIUM 85
TRACER TECHNIQUES
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
STRONTIUM ISOTOPES
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques