In vitro biological effects of volcanic ash from Mount Sakurajima

Journal Article · Tue Jan 01 00:00:00 EST 1985 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398509530724· OSTI ID:6291496

Yano, E; Takeuchi, A; Nishii, S; Koizumi, A; Poole, A; Brown, R C; Johnson, N F; Evans, P H; Yukiyama, Y

Mount Sakurajima in the south of the Kyushu Island of Japan erupts hundreds of times a year and continuously emits large amounts of ash. More than a million people live under this ash plume, and there is considerable concern about the possible effects of this on their health. The authors have studied the physiochemical characteristics and in vitro effects of airborne ash collected at 8 km from the crater. More than 30% of the ash was found to be SiO2 (w/w) with most of the particles within the respirable size range. The ash did not inhibit the colony formation of V79-4 cells and failed to activate complement or generate chemotactic factor activity in samples of fresh human serum. It was minimally active in causing the release of lysosomal enzymes from human neutrophils, and did not cause arachidonic acid release from macrophage-like cells. These results were in accord with our epidemiological study, in which very low prevalences of nonspecific respiratory diseases were demonstrated even at the area with highest ash exposure.

• Research Organization: Teikyo Univ., Tokyo, Japan
• OSTI ID: 6291496
• Journal Information: J. Toxicol. Environ. Health; (United States), Vol. 16:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ASHES
BIOLOGICAL EFFECTS
CHEMICAL PROPERTIES
PHYSICAL PROPERTIES
VOLCANOES
AIR POLLUTION
ANIMAL CELLS
ARACHIDONIC ACID
BLOOD SERUM
COLONY FORMATION
HAMSTERS
IN VITRO
JAPAN
MAN
NEUTROPHILS
PLUMES
SILICON OXIDES
ANIMALS
ASIA
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACIDS
CHALCOGENIDES
LEUKOCYTES
MAMMALS
MATERIALS
MONOCARBOXYLIC ACIDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
POLLUTION
PRIMATES
RESIDUES
RODENTS
SILICON COMPOUNDS
VERTEBRATES
560301* - Chemicals Metabolism & Toxicology- Cells- (-1987)