Radioiodinated maleimides and use as agents for radiolabeling antibodies

Patent · Mon Apr 04 00:00:00 EDT 1988

OSTI ID:6259629

Srivastava, P. C.

A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.

• Research Organization: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
• DOE Contract Number: AC05-84OR21400
• Assignee: Dept. of Energy
• Patent Number(s): PATENTS-US-A7177219
• Application Number: ON: DE89011799
• OSTI ID: 6259629
• Resource Relation: Other Information: Portions of this document are illegible in microfiche products
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
RADIOPHARMACEUTICALS
LABELLING
ANTIBODIES
DIAGNOSTIC TECHNIQUES
INVENTIONS
IODINATION
PROTEINS
THIOLS
CHEMICAL REACTIONS
DRUGS
HALOGENATION
LABELLED COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
400703* - Radiochemistry & Nuclear Chemistry- Radioisotope Production
550200 - Biochemistry