Alveolar deposition of sized particles of /sup 239/PuO/sub 2/ in the mouse

Journal Article · Sat Jan 01 00:00:00 EST 1983 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575946· OSTI ID:6252931

Morgan, A; Black, A; Moores, S R; Pritchard, J N; Walsh, M; Lambert, B E

Data on the alveolar deposition of /sup 239/PuO/sub 2/ particles in the mouse are presented. It is shown that alveolar deposition falls with increasing activity median aerodynamic diameter (AMAD) over the range 0.6 to 2.4 microns. In the mouse, any peak in alveolar deposition must occur at an AMAD of less than 1 micron. Information is also provided on the relative lobar concentrations (RLCs) of /sup 239/PuO/sub 2/. The RLC is greatest in the right apical lobe and increases quite sharply with AMAD. The RLCs of the other lobes of the right lung decline with AMAD. The RLC in the left lobe is relatively unaffected by AMAD.

• Research Organization: Environmental and Medical Sciences Division, AERE, Harwell, Oxon, United Kingdom
• OSTI ID: 6252931
• Journal Information: Radiat. Res.; (United States), Vol. 93:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
LUNGS
RADIONUCLIDE KINETICS
PLUTONIUM 239
TISSUE DISTRIBUTION
DEPOSITION
INHALATION
MICE
PARTICLE SIZE
PLUTONIUM DIOXIDE
ACTINIDE COMPOUNDS
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMALS
BODY
CHALCOGENIDES
DISTRIBUTION
EVEN-ODD NUCLEI
HEAVY NUCLEI
INTAKE
ISOTOPES
MAMMALS
NUCLEI
ORGANS
OXIDES
OXYGEN COMPOUNDS
PLUTONIUM COMPOUNDS
PLUTONIUM ISOTOPES
PLUTONIUM OXIDES
RADIOISOTOPES
RESPIRATORY SYSTEM
RODENTS
SIZE
TRANSURANIUM COMPOUNDS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
551000 - Physiological Systems
560162 - Radionuclide Effects
Kinetics
& Toxicology- Animals
Plants
Microorganisms
& Cells