125I implantation for carcinoma of prostate. Further follow-up of first 100 cases
Analysis of the first 100 patients at the Memorial Sloan-Kettering Cancer Center with Stage B or C prostatic cancer treated by pelvic lymph node dissection and Iodine-125 implantation and endocrine therapy when specifically indicated revealed five-year survival rates of 87 and 77 per cent, respectively. Tumor stage, tumor grade, and lymph node metastasis each correlated with survival, but the latter was the most significant factor. Although routine follow-up biopsies were not performed, local tumor control as judged by serial digital rectal examination defined a prognostically favored group of patients. In the absence of controls, however, whether the latter response indicates a salutary effect of the treatment which produces an improved survival or merely identifies a group of patients who were predetermined to have a more favorable survival is undetermined.
- Research Organization:
- Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York
- OSTI ID:
- 6221957
- Journal Information:
- Urology (Ridgewood, N.J.); (United States), Vol. 20:6
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ENDOCRINE DISEASES
RADIOTHERAPY
PROSTATE
BIOLOGICAL RADIATION EFFECTS
BIOPSY
COMPARATIVE EVALUATIONS
IODINE 125
LYMPH NODES
METASTASES
PATIENTS
RADIATION SOURCE IMPLANTS
SURVIVAL CURVES
TUMOR CELLS
USA
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GLANDS
IMPLANTS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
LYMPHATIC SYSTEM
MALE GENITALS
MEDICINE
NORTH AMERICA
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
THERAPY
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man