Occurrence of aneuploidy for the X chromosome in over 1,300 unrelated specimens screened for the fragile X chromosome
Journal Article
·
· American Journal of Medical Genetics
OSTI ID:62053
An apparent association between the occurrence of the fragile X syndrome and Klinefelter and Down syndromes has been reported over the past few years. We reported 3 cells with extra X chromosomes [XXY (one cell), XXXY (2 cells)] in a fragile X male who exhibited 37 fragile X chromosomes in 200 cells studied. After making this observation, we decided to determine the number of X chromosomes in all fragile X chromosome analyses to see if there was any increased mitotic nondisjunction for the X chromosome. We conclude that there was no association between the fragile X syndrome and X chromosome mitotic nondisjunction/aneuploidy in this group of individuals. 9 refs., 1 tab.
- OSTI ID:
- 62053
- Journal Information:
- American Journal of Medical Genetics, Vol. 51, Issue 4; Other Information: PBD: 15 Jul 1994
- Country of Publication:
- United States
- Language:
- English
Similar Records
Mosaic variegated aneuploidy with microcephaly: A rare cytogenetic syndrome
Elevated frequencies of hyperhaploid sperm were detected in a man with a history of multiple aneuploid pregnancies
New tools for the study of chromosome segregation and aneuploidy at the molecular level
Journal Article
·
Thu Sep 01 00:00:00 EDT 1994
· American Journal of Human Genetics
·
OSTI ID:62053
Elevated frequencies of hyperhaploid sperm were detected in a man with a history of multiple aneuploid pregnancies
Journal Article
·
Wed Oct 01 00:00:00 EDT 1997
· Environmental and Molecular Mutagenesis
·
OSTI ID:62053
New tools for the study of chromosome segregation and aneuploidy at the molecular level
Conference
·
Fri Dec 31 00:00:00 EST 1993
·
OSTI ID:62053
+1 more