Genes for the dimerization cofactor of hepatocyte nuclear factor-1[alpha] (DCOH) are on human and murine chromsomes 10
Journal Article
·
· Genomics; (United States)
- Stanford Univ., CA (United States)
Hepatocyte nuclear factor-1[alpha] (HNF-1[alpha]; gene symbol, TCF1) forms dimers with itself as well as with HNF-1[beta] and regulates the expression of several liver-specific genes. Recently, a dimerization cofactor of hepatocyte nuclear factor-1[alpha], called DCOH, has been identified. Here, the authors report the chromosomal localization of the genes for this cofactor to chromosomes 10 in both humans and mice by Southern blot analyses of somatic cell hybrids. 25 refs., 1 fig., 2 tabs.
- OSTI ID:
- 6179775
- Journal Information:
- Genomics; (United States), Vol. 16:1; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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