Delayed aerodigestive tract complications following combined therapy for thyroid cancer

Journal Article · Sun Sep 01 00:00:00 EDT 1985 · Ann. Otol., Rhinol., Laryngol.; (United States)

OSTI ID:6178924

Grossman, T W; Wilson, J F; Toohill, R J

Radical surgery for papillary adenocarcinoma of the thyroid has been associated with a significant incidence of complications. In some instances, postoperative irradiation is given when there is some suspicion of persistent or occult disease, although thyroid suppression and ablative radioiodine therapy have proved to be very effective adjuvants to surgery. Three patients with papillary adenocarcinoma of the thyroid developed severe, delayed complications 25, 7, and 2 years, respectively, after treatment with primary radical surgery and postoperative irradiation. The degree of injury to the aerodigestive tract as a result of the surgery and irradiation therapy makes treatment difficult regardless of the modality. The possible mechanisms that cause these complications, along with proposed methods of treatment, are discussed.

• Research Organization: Medical College of Wisconsin, Milwaukee
• OSTI ID: 6178924
• Journal Information: Ann. Otol., Rhinol., Laryngol.; (United States), Journal Name: Ann. Otol., Rhinol., Laryngol.; (United States)
• Country of Publication: United States
• Language: English

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DELAYED RADIATION EFFECTS
RADIOTHERAPY
SIDE EFFECTS
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RADIATION EFFECTS
RADIOLOGY
RESPIRATORY SYSTEM
THERAPY
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