Distribution of sup 3 H-proline within transseptal fibers of the rat following release of orthodontic forces

Journal Article · Mon Oct 01 00:00:00 EDT 1990 · American Journal of Anatomy; (USA)

DOI:https://doi.org/10.1002/aja.1001890208· OSTI ID:6171201

Row, K L; Johnson, R B ^[1]

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1. Univ. of Manitoba, Winnipeg (Canada)

Maxillary right first molar teeth of rats were tipped mesially with an orthodontic appliance for 2 weeks (experimental group), {sup 3}H-proline was injected, and orthodontic forces were removed 6 hr later (time 0). The contralateral molar teeth of treated (internal control group) and age- and weight-matched untreated animals (external control group) were also studied. Diastemata were created between the molar teeth by the orthodontic appliance, and transseptal fibers between first and second (P less than 0.001) and second and third molars (P less than 0.005) were significantly lengthened as compared to external and internal controls at time 0. Diastemata between molar teeth were closed 5 days after removal of orthodontic force. Transseptal fibers adjacent to the source of the orthodontic force (mesial region) had the highest mean number of {sup 3}H-proline-labeled proteins at time 0 and at all times following removal of the force (P less than 0.001), and had the highest rate of labeled protein removal (P less than 0.001). Half-lives for removal of 3H-proline-labeled transseptal fiber proteins were significantly greater in mesial and distal regions and significantly less in middle regions of experimentals than in corresponding regions of external controls (P less than 0.001).

• OSTI ID: 6171201
• Journal Information: American Journal of Anatomy; (USA), Vol. 189:2; ISSN 0002-9106
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
PROLINE
BIOSYNTHESIS
TEETH
PROSTHESES
BIOLOGICAL HALF-LIFE
DENTISTRY
RATS
TISSUE DISTRIBUTION
TRACER TECHNIQUES
TRITIUM COMPOUNDS
AMINES
AMINO ACIDS
ANIMALS
AZOLES
CARBOXYLIC ACIDS
DIGESTIVE SYSTEM
DISTRIBUTION
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
ISOTOPE APPLICATIONS
MAMMALS
MEDICAL SUPPLIES
MEDICINE
ORAL CAVITY
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRROLES
PYRROLIDINES
RODENTS
SYNTHESIS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques
550600 - Medicine