Brain and spinal cord hemorrhage in long-term survivors of malignant pediatric brain tumors: A possible late effect of therapy

Journal Article · Tue Jan 01 00:00:00 EST 1991 · Neurology; (USA)

DOI:https://doi.org/10.1212/WNL.41.1.148· OSTI ID:6144513

Allen, J C; Miller, D C; Budzilovich, G N; Epstein, F J ^[1]

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1. NYU Medical Center, NY (USA)

Three children with malignant primary CNS tumors treated with craniospinal radiotherapy developed intraparenchymal hemorrhages a median of 5 years following therapy in sites distant from the primary tumor. Radical surgical procedures disclosed fresh and old hematoma, gliosis, and necrosis in all 3 patients and an aggregation of abnormal microscopic blood vessels in two. No tumor was found. All 3 patients remain in long-term (greater than 10 years) continuous remission.

• OSTI ID: 6144513
• Journal Information: Neurology; (USA), Vol. 41:1; ISSN 0028-3878
• Country of Publication: United States
• Language: English

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