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Title: Radiotherapy of bronchogenic carcinoma: analysis of a treatment schedule designed for use with hyperbaric oxygen. [/sup 60/Co]

Abstract

All cases of bronchogenic carcinoma treated with curative intent over an eight-year period were reviewed. Most were treated with 12 x 400 rad in 32 days using /sup 60/Co, a schedule designed to optimize the radiation-sensitizing properties of hyperbaric oxygen. While O/sub 2/ gave no obvious benefit, overall four-year survival was 10.6% and that of patients with good prognostic indicators was 18%. No radiation myelitis was observed. This protocol delivers an adequate tumor dose and appears to be tolerated well by most patients.

Authors:
; ; ;
Publication Date:
Research Org.:
LDS Hospital, Salt Lake City, UT
OSTI Identifier:
6120491
Resource Type:
Journal Article
Journal Name:
Radiology; (United States)
Additional Journal Information:
Journal Volume: 140:1
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; BIOLOGICAL RADIATION EFFECTS; OXYGEN; RADIOSENSITIVITY EFFECTS; PNEUMONITIS; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; CARCINOMAS; COBALT 60; FRACTIONATED IRRADIATION; GAMMA RADIATION; SURVIVAL TIME; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; ELEMENTS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NONMETALS; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; YEARS LIVING RADIOISOTOPES; 560151* - Radiation Effects on Animals- Man; 550603 - Medicine- External Radiation in Therapy- (1980-)

Citation Formats

Sause, W T, Sweeney, R A, Plenk, H P, and Thomson, J W. Radiotherapy of bronchogenic carcinoma: analysis of a treatment schedule designed for use with hyperbaric oxygen. [/sup 60/Co]. United States: N. p., 1981. Web. doi:10.1148/radiology.140.1.7244227.
Sause, W T, Sweeney, R A, Plenk, H P, & Thomson, J W. Radiotherapy of bronchogenic carcinoma: analysis of a treatment schedule designed for use with hyperbaric oxygen. [/sup 60/Co]. United States. https://doi.org/10.1148/radiology.140.1.7244227
Sause, W T, Sweeney, R A, Plenk, H P, and Thomson, J W. 1981. "Radiotherapy of bronchogenic carcinoma: analysis of a treatment schedule designed for use with hyperbaric oxygen. [/sup 60/Co]". United States. https://doi.org/10.1148/radiology.140.1.7244227.
@article{osti_6120491,
title = {Radiotherapy of bronchogenic carcinoma: analysis of a treatment schedule designed for use with hyperbaric oxygen. [/sup 60/Co]},
author = {Sause, W T and Sweeney, R A and Plenk, H P and Thomson, J W},
abstractNote = {All cases of bronchogenic carcinoma treated with curative intent over an eight-year period were reviewed. Most were treated with 12 x 400 rad in 32 days using /sup 60/Co, a schedule designed to optimize the radiation-sensitizing properties of hyperbaric oxygen. While O/sub 2/ gave no obvious benefit, overall four-year survival was 10.6% and that of patients with good prognostic indicators was 18%. No radiation myelitis was observed. This protocol delivers an adequate tumor dose and appears to be tolerated well by most patients.},
doi = {10.1148/radiology.140.1.7244227},
url = {https://www.osti.gov/biblio/6120491}, journal = {Radiology; (United States)},
number = ,
volume = 140:1,
place = {United States},
year = {Wed Jul 01 00:00:00 EDT 1981},
month = {Wed Jul 01 00:00:00 EDT 1981}
}