Intestinal transport of manganese from human milk, bovine milk and infant formula in rats
The transport of manganese from extrinsically labeled human milk, bovine milk and infant formula was studied by the everted intestinal sac method. Tissue/mucosal flux data indicated that transport of manganese into the intestinal tissue was significantly greater with bovine milk and formula than from human milk. Similarly, the total flux of manganese from the mucosal to serosal surface was less when human milk was used. Smaller molecular weight manganese binding ligands isolated from the milk samples enhanced the mucosal to tissue movement of manganese as contrasted to the higher molecular weight manganese binding ligands. Most significantly the data suggest that the transport and uptake of manganese is less in the presence of human milk and its isolated manganese fractions than it is in bovine milk or infant formula. 15 references, 3 tables.
- Research Organization:
- Univ. of Oklahoma Health Sciences Center, Oklahoma City
- OSTI ID:
- 6093557
- Journal Information:
- Life Sci.; (United States), Vol. 35:24
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
MANGANESE
INTESTINAL ABSORPTION
MILK
SPECIES DIVERSITY
CATTLE
CHEMICAL ANALYSIS
CHEMICAL BONDS
EXPERIMENTAL DATA
INTESTINES
LIGANDS
MAN
MANGANESE 54
RATS
TRACER TECHNIQUES
UPTAKE
ABSORPTION
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DATA
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
FOOD
GASTROINTESTINAL TRACT
INFORMATION
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MANGANESE ISOTOPES
MATERIALS
METALS
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANS
PRIMATES
RADIOISOTOPES
RODENTS
RUMINANTS
TRANSITION ELEMENTS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
551001 - Physiological Systems- Tracer Techniques