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Title: Contrast media: Biologic effects and clinical application

Book ·
OSTI ID:6074526

An overview is presented of the recent developments in contrast media and their clinical applications, plus the current state-of-the-art in computerized tomography, digital subtraction angiography, ultrasound and magnetic resonance imaging (MRI). Contents of these volumes include: an in-depth review of the historical development, modern perspectives in structure-function relationships, biologic effects on hemostats, gastrointestinal, cardiovascular systems and drug interactions. Critical and basic issues, including cellular toxicity, mutagenesis, synergism between radiation and contrast agents, mechanisms in contrast-induced reactions, and the management of such reactions in high-risk patients are also presented. Specific applications of paramagnetic compounds in MRI and the recent concept of liposome-encapsulated and particulate suspension of contrast materials in diagnostic imaging are thoroughly discussed.

OSTI ID:
6074526
Country of Publication:
United States
Language:
English

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