Extremely low frequency pulsed electromagnetic fields increase cell proliferation in lymphocytes from young and aged subjects
The effect of the in vitro exposure to extremely low frequency pulsed electromagnetic fields (PEMFs) on the proliferation of human lymphocytes from 24 young and 24 old subjects was studied. The exposure to PEMFs during a 3-days culture period or during the first 24 hours was able to increase phytohaemagglutinin-induced lymphocyte proliferation in both groups. Such effect was greater in lymphocytes from old people which showed a markedly reduced proliferative capability and, after PEMF exposure, reached values of /sup 3/H-TdR incorporation similar to those of young subjects. The relevance of these data for the understanding and the reversibility of the proliferative defects in cells from aged subjects and for the assessment of risk related to the environmental exposure to PEMFs has to be considered.
- Research Organization:
- Univ. of Modena (Italy)
- OSTI ID:
- 6070250
- Journal Information:
- Biochem. Biophys. Res. Commun.; (United States), Vol. 160:2
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
ELECTROMAGNETIC FIELDS
BIOLOGICAL EFFECTS
LYMPHOCYTES
CELL PROLIFERATION
AGE DEPENDENCE
CELL CULTURES
MAN
PHYTOHEMAGGLUTININ
THYMIDINE
TRACER TECHNIQUES
TRITIUM COMPOUNDS
AGGLUTININS
ANIMAL CELLS
ANIMALS
ANTIBODIES
AZINES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOHYDRATES
CONNECTIVE TISSUE CELLS
HEMAGGLUTININS
HETEROCYCLIC COMPOUNDS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LEUKOCYTES
MAMMALS
MATERIALS
MITOGENS
MUCOPROTEINS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
POLYSACCHARIDES
PRIMATES
PROTEINS
PYRIMIDINES
RIBOSIDES
SACCHARIDES
SOMATIC CELLS
VERTEBRATES
560400* - Other Environmental Pollutant Effects
550201 - Biochemistry- Tracer Techniques