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Title: Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment

Abstract

A new, miniature cesium iodide/photodiode nuclear probe (the Cardioscint) has been developed for continuous on-line measurement of left ventricular function and the ST-segment. Ejection fraction (EF) measurements in 77 patients were compared with gated equilibrium radionuclide ventriculograms. The probe was positioned over the left ventricle by first using a blind positioning algorithm and then by using the gamma camera. Background was measured both manually and automatically. There was good correlation between probe (positioned blind) and gamma camera EF with both manual (r = 0.80, n = 65) and automatic (r = 0.78, n = 66) backgrounds. Use of the gamma camera did not significantly alter the results. Correlation between the probe stroke counts and thermodilution-derived stroke index during atrial pacing in six subjects was also satisfactory (r = 0.69, n = 102). Thus, the Cardioscint is able to provide a reliable estimate of EF and can track rapid changes in cardiac volumes.

Authors:
; ; ; ;  [1]
  1. Northwick Park Hospital, Harrow, Middlesex (England)
Publication Date:
OSTI Identifier:
6056048
Resource Type:
Journal Article
Journal Name:
Journal of Nuclear Medicine; (USA)
Additional Journal Information:
Journal Volume: 32:1; Journal ID: ISSN 0161-5505
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARDIOVASCULAR DISEASES; DIAGNOSIS; HEART; DYNAMIC FUNCTION STUDIES; ALGORITHMS; CESIUM ISOTOPES; GAMMA CAMERAS; RADIOISOTOPE SCANNING; SCINTILLATION COUNTING; ALKALI METAL ISOTOPES; BODY; CAMERAS; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DISEASES; ISOTOPES; MATHEMATICAL LOGIC; ORGANS; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Broadhurst, P, Cashman, P, Crawley, J, Raftery, E, and Lahiri, A. Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment. United States: N. p., 1991. Web.
Broadhurst, P, Cashman, P, Crawley, J, Raftery, E, & Lahiri, A. Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment. United States.
Broadhurst, P, Cashman, P, Crawley, J, Raftery, E, and Lahiri, A. 1991. "Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment". United States.
@article{osti_6056048,
title = {Clinical validation of a miniature nuclear probe system for continuous on-line monitoring of cardiac function and ST-segment},
author = {Broadhurst, P and Cashman, P and Crawley, J and Raftery, E and Lahiri, A},
abstractNote = {A new, miniature cesium iodide/photodiode nuclear probe (the Cardioscint) has been developed for continuous on-line measurement of left ventricular function and the ST-segment. Ejection fraction (EF) measurements in 77 patients were compared with gated equilibrium radionuclide ventriculograms. The probe was positioned over the left ventricle by first using a blind positioning algorithm and then by using the gamma camera. Background was measured both manually and automatically. There was good correlation between probe (positioned blind) and gamma camera EF with both manual (r = 0.80, n = 65) and automatic (r = 0.78, n = 66) backgrounds. Use of the gamma camera did not significantly alter the results. Correlation between the probe stroke counts and thermodilution-derived stroke index during atrial pacing in six subjects was also satisfactory (r = 0.69, n = 102). Thus, the Cardioscint is able to provide a reliable estimate of EF and can track rapid changes in cardiac volumes.},
doi = {},
url = {https://www.osti.gov/biblio/6056048}, journal = {Journal of Nuclear Medicine; (USA)},
issn = {0161-5505},
number = ,
volume = 32:1,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 1991},
month = {Tue Jan 01 00:00:00 EST 1991}
}