Cytogenetic findings in persons living near the Love Canal

Journal Article · Fri Mar 16 00:00:00 EST 1984 · JAMA, J. Am. Med. Assoc.; (United States)

DOI:https://doi.org/10.1001/jama.251.11.1437· OSTI ID:6051103

Heath, Jr, C W; Nadel, M R; Zack, Jr, M M; Chen, A T.L.; Bender, M A; Preston, R J

Cytogenetic analyses were performed on peripheral blood from 46 present or past residents of the areas surrounding Love Canal, a former dump site for chemical wastes in Niagara Falls, NY. Participants included 17 persons in whom cytogenetic analyses had been performed in 1980 and 29 persons who had been living in 1978 in seven homes that directly adjoined the canal and in which environmental tests showed elevated levels of chemicals spreading from the canal. Frequencies of chromosomal aberrations and of sister chromatid exchange (SCE) did not differ significantly from control levels. For all participants, cigarette smoking was associated with an increase in sister chromatid exchange frequency.

• Research Organization: Centers for Disease Control, Atlanta, GA
• DOE Contract Number: AC02-76CH00016; W-7405-ENG-26
• OSTI ID: 6051103
• Journal Information: JAMA, J. Am. Med. Assoc.; (United States), Vol. 251:11
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BENZENE
GENETIC EFFECTS
CHLORINATED AROMATIC HYDROCARBONS
CHROMOSOMAL ABERRATIONS
TOBACCO SMOKES
TOLUENE
XYLENES
CHEMICAL EFFLUENTS
ENVIRONMENTAL TRANSPORT
EXPERIMENTAL DATA
HAZARDOUS MATERIALS
HOUSES
HUMAN POPULATIONS
AEROSOLS
ALKYLATED AROMATICS
AROMATICS
BIOLOGICAL EFFECTS
BUILDINGS
COLLOIDS
DATA
DISPERSIONS
HALOGENATED AROMATIC HYDROCARBONS
HYDROCARBONS
INFORMATION
MASS TRANSFER
MATERIALS
MUTATIONS
NUMERICAL DATA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POPULATIONS
RESIDENTIAL BUILDINGS
RESIDUES
SMOKES
SOLS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)