Fatty infiltration of the liver: evaluation by proton spectroscopic imaging
The reliability of proton spectroscopic imaging in evaluating fatty infiltration of the liver was investigated in 35 subjects (12 healthy volunteers and 23 patients with fatty livers). With this modified spin-echo technique, fatty liver could be separated from normal liver both visually and quantitatively. On the opposed image, normal liver had an intermediate signal intensity, greater than that of muscle, whereas fatty liver had a lower signal intensity, equal to or less than that of muscle. In normal livers, the lipid signal fraction was less than 10%, while in fatty livers it was greater than 10% and usually exceeded 20%. With this technique, nonuniform fatty infiltration of the liver can be differentiated from hepatic metastases, and the technique may prove useful in the differentiation of some hepatic disorders.
- Research Organization:
- Washington Univ. School of Medicine, St. Louis, MO
- OSTI ID:
- 6042498
- Journal Information:
- Radiology; (United States), Vol. 3
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
LIVER
NUCLEAR MAGNETIC RESONANCE
METABOLIC DISEASES
DIAGNOSIS
METASTASES
LIPIDS
PATIENTS
PROTONS
BARYONS
BODY
DIGESTIVE SYSTEM
DISEASES
ELEMENTARY PARTICLES
FERMIONS
GLANDS
HADRONS
MAGNETIC RESONANCE
NUCLEONS
ORGANIC COMPOUNDS
ORGANS
RESONANCE
550602* - Medicine- External Radiation in Diagnostics- (1980-)