Cytogenetics of human sperm: Structural aberrations and DNA replication
Conference
·
OSTI ID:6036838
The human sperm-hamster egg system, first introduced in 1978 (Rudak et al), has yielded some important insights into questions on chromosomal integrity of human sperm. In this system, human sperm are co-incubated with eggs from the golden hamster. After the gametes fuse, eggs are cultured overnight and approximately 15 hours after fusion, display the haploid chromosomal complement of individual human sperm cells. These chromosomes can be analyzed by standard banding techniques to identify and quantify structural and numerical abnormalities in single sperm. 32 refs., 1 fig.
- Research Organization:
- Lawrence Livermore National Lab., CA (USA)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 6036838
- Report Number(s):
- UCRL-101502; CONF-8907113-4; ON: DE89015330
- Resource Relation:
- Conference: 5. international conference on environmental mutagens, Cleveland, OH, USA, 10-15 Jul 1989; Other Information: Portions of this document are illegible in microfiche products
- Country of Publication:
- United States
- Language:
- English
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