Indicators of lead, zinc and cadmium exposure in cattle. I. Results in a polluted area
Dairy cattle on a farm located in the vicinity of a lead and zinc-ore processing factory were studied over 21 mo and compared with cattle on a control farm. Mean daily intakes of lead from the diet were 4.3 mg/kg body weight, with great variations; mean daily zinc intakes were 5.6 mg/kg body weight; and mean daily cadmium intakes were 0.064 mg/kg body weight. The 3 major indicators of contamination were blood lead concentrations, with mean values of 50 micrograms/100 ml of blood, zinc protoporphyrin with mean values of 165 micrograms/100 ml blood, and lead concentrations in hair which averaged 10 micrograms/g. Blood zinc concentrations and zinc concentrations were not significantly increased. One cow developed fatal post-partum paralysis. Liver, kidney and bone lead concentrations and kidney cadmium concentrations were good ''post-mortem'' indicators of exposure.
- Research Organization:
- National Veterinary School Alfort, Maisons-Alfort (France)
- OSTI ID:
- 6020905
- Journal Information:
- Vet. Hum. Toxicol.; (United States), Vol. 30:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CADMIUM
TISSUE DISTRIBUTION
CATTLE
CONTAMINATION
LEAD
ZINC
BIOLOGICAL INDICATORS
BLOOD
DIET
HAIR
HEMOGLOBIN
KIDNEYS
PROTOPORPHYRINS
SKELETON
ANIMALS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CARBOXYLIC ACIDS
DISTRIBUTION
DOMESTIC ANIMALS
ELEMENTS
GLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
MAMMALS
MATERIALS
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PIGMENTS
PORPHYRINS
PROTEINS
RUMINANTS
SKIN
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology