Aplastic anemia and red cell aplasia due to pentachlorophenol

Journal Article · Sat Jan 01 00:00:00 EST 1983 · South. Med. J.; (United States)

DOI:https://doi.org/10.1097/00007611-198301000-00013· OSTI ID:5990685

Roberts, H J

Repeated exposure to commercial (technical grade) pentachlorophenol (PCP) preceded aplastic anemia in four patients and pure red cell aplasia in two. Two patients developed concomitant or subsequent Hodgkin's disease and acute leukemia. The hematologic, mutagenic, and carcinogenic effect of PCP and its chemical contaminants have been documented in other clinical and experimental reports. In view of the widespread contamination of our environment by PCP, clinicians and public health investigators must seek out such exposure in these and related disorders and initiate measures to reduce it.

• Research Organization: Mannow Research Laboratory, Palm Beach Institute for Medical Research, West Palm Beach, FL
• OSTI ID: 5990685
• Journal Information: South. Med. J.; (United States), Vol. 76:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
HEMATOPOIETIC SYSTEM
SENSITIVITY
PHENOLS
HEALTH HAZARDS
ANEMIAS
HODGKINS DISEASE
LEUKEMIA
PATHOLOGY
PATIENTS
PUBLIC HEALTH
AROMATICS
BODY
DISEASES
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HEMIC DISEASES
HYDROXY COMPOUNDS
LYMPHOMAS
NEOPLASMS
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560306* - Chemicals Metabolism & Toxicology- Man- (-1987)