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Title: Effect of medical x-ray exposure on subsequent reproductive outcomes in scoliosis patients

Thesis/Dissertation ·
OSTI ID:5986634

A retrospective cohort study was done which was designed to assess the effects of medical x-ray exposure on cancer incidence among scoliosis patients. Although the primary purpose of the study was to assess cancer incidence, a secondary goal was to investigate whether diagnostic x-ray exposure is related to adverse reproductive events in the female subjects. A series of case-control analyses were done which were designed to assess these effects. Radiation exposure was measured both by total films received and by an estimate of the number of films received and by an estimate of the number of films which involved ovarian irradiation. Radiation appeared to increase a woman's risk of any adverse event in the overall analysis and her risk of a premature or low birth weight infant in the separate analyses. Radiation did not appear to be related to spontaneous abortion, complications of pregnancy or delivery or birth defects, although the results of the pregnancy complications analysis was suggestive.

Research Organization:
Minnesota Univ., Minneapolis (USA)
OSTI ID:
5986634
Resource Relation:
Other Information: Thesis (Ph. D.)
Country of Publication:
United States
Language:
English