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Title: Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease (in Chinese)

Abstract

In China, endemic regions of Kaschin-Beck's disease, Keshan disease, and animal white muscle disease basically overlap, mainly the transitional area between the moist Southeast and the arid Northwest. Tests conducted by the authors reveal that the selenium content of major soils of the regions affected by the diseases is 0.088 to 0.360 ppM, that of the grains below 20 to 30 ppB. Of the inhabitants, 94 percent have serum selenium content below 0.031 ..mu..g/l and the selenium content of the hair of inhabitants is 100 to 200 ppB. From July 1979 to June 1980, the authors treated 41 cases of Kaschin-Beck's disease with sodium selenite-V/sub E/ and 36 of them recovered from the disease. Based upon these data, the authors believe that environmental selenium deficiency of these regions is perhaps the cause of the low level selenium nutrition of the inhabitants. The low level selenium nutrition in turn leads to a reduction of certain enzymic activity to cause the Kaschin-Beck's disease, as well as the Keshan disease and the animal white muscle disease.

Authors:
;
Publication Date:
OSTI Identifier:
5983304
Resource Type:
Journal Article
Journal Name:
J. Environ. Sci.; (United States)
Additional Journal Information:
Journal Volume: 3:2
Country of Publication:
United States
Language:
Chinese
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 54 ENVIRONMENTAL SCIENCES; METABOLIC DISEASES; PATHOLOGY; SELENIUM; ECOLOGICAL CONCENTRATION; METABOLISM; CEREALS; DIET; ENZYME ACTIVITY; FOOD CHAINS; HUMAN POPULATIONS; NUTRITION; NUTRITIONAL DEFICIENCY; REGIONAL ANALYSIS; SEEDS; VITAMIN E; DISEASES; ELEMENTS; GRAMINEAE; GRASS; PLANTS; POPULATIONS; SEMIMETALS; VITAMINS; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 510302 - Environment, Terrestrial- Radioactive Materials Monitoring & Transport- Terrestrial Ecosystems & Food Chains- (-1987)

Citation Formats

Hou, S, and Zhu, Z. Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease. United States: N. p., 1982. Web.
Hou, S, & Zhu, Z. Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease. United States.
Hou, S, and Zhu, Z. 1982. "Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease". United States.
@article{osti_5983304,
title = {Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease},
author = {Hou, S and Zhu, Z},
abstractNote = {In China, endemic regions of Kaschin-Beck's disease, Keshan disease, and animal white muscle disease basically overlap, mainly the transitional area between the moist Southeast and the arid Northwest. Tests conducted by the authors reveal that the selenium content of major soils of the regions affected by the diseases is 0.088 to 0.360 ppM, that of the grains below 20 to 30 ppB. Of the inhabitants, 94 percent have serum selenium content below 0.031 ..mu..g/l and the selenium content of the hair of inhabitants is 100 to 200 ppB. From July 1979 to June 1980, the authors treated 41 cases of Kaschin-Beck's disease with sodium selenite-V/sub E/ and 36 of them recovered from the disease. Based upon these data, the authors believe that environmental selenium deficiency of these regions is perhaps the cause of the low level selenium nutrition of the inhabitants. The low level selenium nutrition in turn leads to a reduction of certain enzymic activity to cause the Kaschin-Beck's disease, as well as the Keshan disease and the animal white muscle disease.},
doi = {},
url = {https://www.osti.gov/biblio/5983304}, journal = {J. Environ. Sci.; (United States)},
number = ,
volume = 3:2,
place = {United States},
year = {Fri Apr 30 00:00:00 EDT 1982},
month = {Fri Apr 30 00:00:00 EDT 1982}
}