Bifunctional mechanism of catalysis in reactions leading to formation of /alpha/-amino ketones

Journal Article · Thu Oct 20 00:00:00 EDT 1988 · J. Org. Chem. USSR (Engl. Transl.); (United States)

OSTI ID:5971613

Popov, A F; Anikeev, A V

The kinetics of the reaction of /alpha/-bromoacetophenone and benzyl bromide with aniline and pyridine in the presence of additions of acetic acid and phenol in benzene at 30/degree/C were investigated. The catalytic effects due to the activity of the uncombined forms of the catalyst, their dimers, and their 1:1 complexes with the amines were separated quantitatively. The change in the catalytic activity of the respective particles in the solutions with variation in the structure of the reagents is examined, and possible mechanisms for the catalytic reactions are discussed on this basis. It is concluded that there is a bifunctional mechanism of catalysis by acetic acid in the reaction of /alpha/-bromoacetophenone with aniline.

• Research Organization: Institute of Physical Chemistry and Coal Chemistry, Donetsk (USSR)
• OSTI ID: 5971613
• Journal Information: J. Org. Chem. USSR (Engl. Transl.); (United States), Vol. 24:5; Other Information: Translated from Zh. Org. Khim.; 24: No. 5, 1046-1050 (May 1988)
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ACETIC ACID
CATALYTIC EFFECTS
ACETOPHENONE
CATALYSIS
ANILINE
BROMINATED AROMATIC HYDROCARBONS
PHENOL
PYRIDINE
AMINES
CATALYSTS
CHEMICAL REACTION KINETICS
COMPLEXOMETRY
DIMERIZATION
KINETIC EQUATIONS
MOLECULAR STRUCTURE
POTENTIOMETRY
AROMATICS
AZINES
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
EQUATIONS
HALOGENATED AROMATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
KETONES
KINETICS
MONOCARBOXYLIC ACIDS
ORGANIC ACIDS
ORGANIC BROMINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHENOLS
POLYMERIZATION
PYRIDINES
REACTION KINETICS
TITRATION
400201* - Chemical & Physicochemical Properties