Fourier ventricular amplitude ratio to evaluate atrial septal defect
First harmonic Fourier analysis of gated blood pool scans results in the formation of two functional images, a phase and amplitude image. The authors have previously shown that the total amplitude values of the two ventricles can be used to quantitate valvular insufficiency. The ventricular amplitude ratio (VAR, left/right) in normals is 1.14 0.11 and patients with valvular insufficiency is elevated (0.3 0.77). In patients with atrial septal defect (ASD), the right ventricle has a larger stroke volume than the left ventricle, and the VAR should be less than unity. To evaluate whether the amplitude image would permit quantification of shunt flow in ASD, the authors compared the VAR to the OP/QS ratio determined by cardiac catheterization (cath) in 3 groups of patients; group I (n=9) had ASD without valvular insufficiency (one patient had right-to-left shunting due to tricuspid stenosis; group II (n=4) had ventricular septal defect; and group III (n=2) had ASD plus valvular insufficiency. QP/QS shunt flow is also determined in group I using standard first-pass radionuclide angiography (rna). The data suggest that the VAR technique accurately determines the magnitude of shunt flow in ASD patients without concomitant valvular insufficiency.
- Research Organization:
- Hospital of the Univ. of Pennsylvania, Philadelphia, PA
- OSTI ID:
- 5971506
- Report Number(s):
- CONF-850611-; TRN: 87-039568
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
BLOOD FLOW
RADIOISOTOPE SCANNING
BLOOD VESSELS
IMAGE PROCESSING
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CORRELATIONS
DYNAMIC FUNCTION STUDIES
FOURIER ANALYSIS
HEART
LABELLED POOL TECHNIQUES
PROSTHESES
SCINTISCANNING
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
ISOTOPE APPLICATIONS
MEDICAL SUPPLIES
ORGANS
PROCESSING
TRACER TECHNIQUES
550602* - Medicine- External Radiation in Diagnostics- (1980-)
551001 - Physiological Systems- Tracer Techniques