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Title: Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment

Abstract

To assess myocardial performance in diabetics following acute myocardial infarction (AMI), resting gated radionuclide studies with Tc-99m were performed within two weeks of the onset of symptoms in matched groups of 18 type-II diabetics with their first clinical AMI (D-AMI), 20 nondiabetics with their first AMI (ND-AMI), and 20 nondiabetic noncardiac controls. Eighty-three percent of D-AMI and 50% of ND-AMI had left ventricular ejection fractions below 2 SD of normal. Diabetics had a significantly lower resting LVEF than nondiabetics (p<0.05). All patients with LVEF < 35% were diabetics. LV mean ejection and filling rates were similar in diabetics and nondiabetics. While 72% of diabetics showed abnormal wall motion in 5 or more segments (out of 9), only 45% of the nondiabetics were this extensively affected. Seventy-two percent of the diabetics showed one or more of akinesis and 39% had one or more areas of dyskinesis, compared to 30% and 5% of the nondiabetics respectively. The authors conclude that the extent, as well as the severity of the left ventricular impairment is more evident in the diabetics than in the nondiabetics, following the first acute MI.

Authors:
; ; ; ;
Publication Date:
Research Org.:
V.A. Med. Ctr., Newington
OSTI Identifier:
5960731
Report Number(s):
CONF-850611-
Journal ID: CODEN: JNMEA; TRN: 87-039288
Resource Type:
Conference
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; HEART; DYNAMIC FUNCTION STUDIES; PATHOLOGICAL CHANGES; SCINTISCANNING; MYOCARDIAL INFARCTION; DIAGNOSIS; MYOCARDIUM; TECHNETIUM 99; DIAGNOSTIC USES; CARDIOVASCULAR DISEASES; CORRELATIONS; DIABETES MELLITUS; PATIENTS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE DISEASES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; METABOLIC DISEASES; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; USES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 551001 - Physiological Systems- Tracer Techniques; 550901 - Pathology- Tracer Techniques

Citation Formats

Amin, E M, Karimeddini, M K, El-Haieg, M O, Dey, H M, and Antar, M A. Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment. United States: N. p., 1985. Web.
Amin, E M, Karimeddini, M K, El-Haieg, M O, Dey, H M, & Antar, M A. Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment. United States.
Amin, E M, Karimeddini, M K, El-Haieg, M O, Dey, H M, and Antar, M A. 1985. "Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment". United States.
@article{osti_5960731,
title = {Left ventricular performance in type-II diabetics with first acute myocardial infarction: A radionuclide assessment},
author = {Amin, E M and Karimeddini, M K and El-Haieg, M O and Dey, H M and Antar, M A},
abstractNote = {To assess myocardial performance in diabetics following acute myocardial infarction (AMI), resting gated radionuclide studies with Tc-99m were performed within two weeks of the onset of symptoms in matched groups of 18 type-II diabetics with their first clinical AMI (D-AMI), 20 nondiabetics with their first AMI (ND-AMI), and 20 nondiabetic noncardiac controls. Eighty-three percent of D-AMI and 50% of ND-AMI had left ventricular ejection fractions below 2 SD of normal. Diabetics had a significantly lower resting LVEF than nondiabetics (p<0.05). All patients with LVEF < 35% were diabetics. LV mean ejection and filling rates were similar in diabetics and nondiabetics. While 72% of diabetics showed abnormal wall motion in 5 or more segments (out of 9), only 45% of the nondiabetics were this extensively affected. Seventy-two percent of the diabetics showed one or more of akinesis and 39% had one or more areas of dyskinesis, compared to 30% and 5% of the nondiabetics respectively. The authors conclude that the extent, as well as the severity of the left ventricular impairment is more evident in the diabetics than in the nondiabetics, following the first acute MI.},
doi = {},
url = {https://www.osti.gov/biblio/5960731}, journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 26:5,
place = {United States},
year = {Wed May 01 00:00:00 EDT 1985},
month = {Wed May 01 00:00:00 EDT 1985}
}

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