Clinical use of indium-111 labeled blood products

Journal Article · Sun Dec 01 00:00:00 EST 1985 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198512000-00024· OSTI ID:5943489

Loken, M K; Clay, M E; Carpenter, R T; Boudreau, R J; McCullough, J J

Following the introduction of In-111 oxine as a label for blood cells by McAffee and Thakur in 1976, these procedures have become increasingly important in the practice of nuclear medicine. Of particular interest are studies involving the use of labeled leukocytes for the detection of focal infection. The clinical utility of labeled platelets is less well developed, although the use of platelets to detect the formation of thrombi in blood vessels and on vascular grafts and prostheses is gaining prominence. This report summarizes the techniques presently employed at the University of Minnesota for the labeling of blood products, and their clinical use. Consideration also is given to the desired expertise and cost factors involved in the labeling of leukocytes and platelets.43 references.

• Research Organization: Univ. of Minnesota Hospital, Minneapolis
• OSTI ID: 5943489
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 12
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
BLOOD PLATELETS
LABELLING
EMBOLI
DIAGNOSIS
LEUKOCYTES
ABDOMEN
DIAGNOSTIC USES
DOGS
INDIUM 111
KINETICS
QUALITY CONTROL
RADIOCHEMISTRY
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY AREAS
BODY FLUIDS
CHEMISTRY
CONTROL
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
USES
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials