Factors affecting bioabsorption, metabolism, and storage of organic compounds by aquatic biota
Biological concentration and transfer of organic chemicals through aquatic food webs can be influenced by a variety of environmental, biological, and biochemical factors. Bioaccumulation can be significantly altered by the presence of suspended matter or complex organic mixtures in the water column. In addition, the bioaccumulation factor of a compound is dependent on the species of an organism, its life stage, and the available food supply. Metabolic changes in structure of absorbed organics can alter both the rate and the mechanism of absorption and elimination of organics. In the case of quinoline absorption by trout, both the rate of absorption and the metabolic disposition depended upon whether exposure was through ingestion or through direct water column exposure. All of these factors can be used to explain why the physical properties of organic compounds (most notably octanol/water partition coefficients) are unreliable predictors of bioaccumulation potential. 24 refs., 1 tab.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 5938194
- Report Number(s):
- PNL-SA-13187; CONF-851027-9; ON: DE86007726
- Resource Relation:
- Conference: 24. Hanford life sciences symposium and environmental research on complex organic mixtures, Richland, WA, USA, 20 Oct 1985
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
ANILINE
BIOLOGICAL ACCUMULATION
PHENOL
PHENOLS
QUINOLINES
AQUATIC ECOSYSTEMS
METABOLITES
TRACER TECHNIQUES
TROUT
AMINES
ANIMALS
AQUATIC ORGANISMS
AROMATICS
AZAARENES
AZINES
ECOSYSTEMS
FISHES
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
ISOTOPE APPLICATIONS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PYRIDINES
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
550501 - Metabolism- Tracer Techniques