Effectiveness of skin absorption of tincture of I in blocking radioiodine from the human thyroid gland

Journal Article · Thu Jun 01 00:00:00 EDT 1989 · Health Phys.; (United States)

DOI:https://doi.org/10.1097/00004032-198906000-00009· OSTI ID:5927254

Miller, K L; Coen, P E; White, W J; Hurst, W J; Achey, B E; Lang, C M

Topical application of tincture of iodine (I) was found to be effective in blocking the thyroid uptake of orally administered /sup 131/I in humans. Abdominal skin application of tincture of I resulted in an approximately 82% reduction in the uptake of /sup 131/I by the thyroid gland. The effectiveness varied among individuals and may have depended on the quantity applied and on the application site. In each study group, elevated levels of serum I were observed.

• Research Organization: Pennsylvania State Univ., Hershey (USA)
• OSTI ID: 5927254
• Journal Information: Health Phys.; (United States), Vol. 56:6
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
IODINE
RADIOSENSITIVITY EFFECTS
IODINE 131
SKIN ABSORPTION
THYROID
RADIONUCLIDE KINETICS
SOLUTIONS
UPTAKE
ABSORPTION
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISPERSIONS
ELEMENTS
ENDOCRINE GLANDS
GLANDS
HALOGENS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MIXTURES
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man