Autoradiographic evidence of sup 125 I-. beta. -endorphin binding sites in the articular cartilage of the rat

Journal Article · Tue Jan 01 00:00:00 EST 1991 · Life Sciences; (United States)

OSTI ID:5909775

Castano, M T; Freire-Garabal, M; Giraldez, M; Nunez, M J; Belmonte, A; Couceiro, J; Jorge, J ^[1]

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1. Univ. of Santiago (Spain)

After {sup 125}I-{beta}-endorphin was intravenously injected to rats, an autoradiographic study of distal femur articular cartilage was performed. Results show a specific binding of {sup 125}I-{beta}-endorphin to chondrocytes, suggesting the possible existence of an opiate modulation of articular cartilage.

• OSTI ID: 5909775
• Journal Information: Life Sciences; (United States), Vol. 49:15; ISSN 0024-3205
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ENDORPHINS
RECEPTORS
BIOLOGICAL LOCALIZATION
AUTORADIOGRAPHY
BIOCHEMICAL REACTION KINETICS
CARTILAGE
FEMUR
INTRAVENOUS INJECTION
IODINE 125
ANIMAL TISSUES
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BODY
CONNECTIVE TISSUE
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE ISOTOPES
ISOTOPES
KINETICS
MEMBRANE PROTEINS
NEUROREGULATORS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOISOTOPES
REACTION KINETICS
SKELETON
TISSUES
550201* - Biochemistry- Tracer Techniques