Monte Carlo techniques for neutron capture therapy

Conference · Tue Jan 01 00:00:00 EST 1991 · Transactions of the American Nuclear Society; (United States)

OSTI ID:5907355

Wheeler, F J ^[1]

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1. Idaho National Engineering Lab., Idaho Falls (United States)

At the Idaho National Engineering Laboratory, the current emphasis in neutron capture therapy (NCT) research is on treatment of glioblastoma multiforme using an administered {sup 10}B-containing drug followed by irradiation in an epithermal neutron beam. in appropriate subjects, the brain tumor selectively uptakes the {sup 10}B, and thermal-neutron flux generated in the tissue causes destruction of tumor cells via {sup 10}B (n,{alpha}){sup 7}Li reactions. Unlike applications of conventional photon therapy where simple methods can be used to calculate absorbed dose, NCT requires a rigorous three-dimensional solution of the Boltzmann transport equation for each unique application. This paper outlines new methods developed for the rtt-MC Monte Carlo code to address the unique requirements of NCT.

• OSTI ID: 5907355
• Report Number(s): CONF-910603-; CODEN: TANSA
• Journal Information: Transactions of the American Nuclear Society; (United States), Vol. 63; Conference: Annual meeting of the American Nuclear Society (ANS), Orlando, FL (United States), 2-6 Jun 1991; ISSN 0003-018X
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
GLIOMAS
NEUTRON CAPTURE THERAPY
DOSIMETRY
BOLTZMANN EQUATION
BORON 10 TARGET
CALCULATION METHODS
CAPTURE
EPITHERMAL NEUTRONS
GEOMETRY
IDAHO NATIONAL ENGINEERING LABORATORY
IRRADIATION
MONTE CARLO METHOD
NEUTRON FLUX
NEUTRON REACTIONS
NUCLEAR MEDICINE
RADIATION DOSES
THREE-DIMENSIONAL CALCULATIONS
UPTAKE
BARYON REACTIONS
BARYONS
DIFFERENTIAL EQUATIONS
DISEASES
DOSES
ELEMENTARY PARTICLES
EQUATIONS
FERMIONS
HADRON REACTIONS
HADRONS
MATHEMATICS
MEDICINE
NATIONAL ORGANIZATIONS
NEOPLASMS
NEUTRON THERAPY
NEUTRONS
NUCLEAR REACTIONS
NUCLEON REACTIONS
NUCLEONS
PARTIAL DIFFERENTIAL EQUATIONS
RADIATION FLUX
RADIOLOGY
RADIOTHERAPY
TARGETS
THERAPY
US DOE
US ERDA
US ORGANIZATIONS
550603* - Medicine- External Radiation in Therapy- (1980-)