Glycol ethers - validation procedures for tube/pump and dosimeter monitoring methods

Journal Article · Fri Jun 01 00:00:00 EDT 1984 · Am. Ind. Hyg. Assoc. J.; (United States)

DOI:https://doi.org/10.1080/15298668491400034· OSTI ID:5904108

Langhorst, M L

Methods were developed and validated for personal monitoring of exposures to airborne glycol ethers, both short-term and long-term time-weighted-averages. Either a 600 mg charcoal tube or a 780 mg silica gel tube is recommended for monitoring nine glycol ethers, depending upon the humidity and other organic compounds to be monitored. The charcoal tube allows maximum sensitivity and is unaffected by high humidity conditions. Two-phase solvent desorption with CS/sub 2/ and water allows aqueous phase recoveries of DOWANOLEM, EM, PM, EE, DM, DPM, and TM glycol ethers. DOWANOL EB, DB, and TPM glycol ethers are partitioned between the two layers, necessitating chromatographic analysis of both layers. The silica gel tube method can be used to monitor all nine glycol ethers tested, but is affected by high humidity conditions, resulting in significant breakthrough of th more volatile glycol ethers. The 3M organic vapor monitor can accurately and conveniently determine exposure concentrations for DOWANOL EM, EE, and PM glycol ethers, but sensitivities may be inadequate for sampling periods less than one hour. These methods were validated at levels down to 0.1 times the Dow internal exposure guidelines for those substances with DOW exposure guidelines and well above the current ACGIH and OSHA guidelines. This paper also illustrates validation procedures for tube/pump and dosimeter methods allowing good definition of method accuracy and precision. Some screening experiments are described for diffusional dosimeters to check the most important parameters in a minimum of time. This methodology will allow assessment of human airborne exposures relative to the new toxicology data avilable on animals.

• Research Organization: Dow Chemical Co., Midland, MI
• OSTI ID: 5904108
• Journal Information: Am. Ind. Hyg. Assoc. J.; (United States), Vol. 45:6
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GLYCOLS
MEASURING METHODS
PERSONNEL MONITORING
PHYSICAL PROPERTIES
ACCURACY
AIR POLLUTION
DATA COMPILATION
HUMIDITY
OCCUPATIONAL EXPOSURE
RECOMMENDATIONS
RESPONSE MODIFYING FACTORS
SAMPLING
VALIDATION
ALCOHOLS
DATA
HYDROXY COMPOUNDS
INFORMATION
MONITORING
NUMERICAL DATA
ORGANIC COMPOUNDS
POLLUTION
RADIATION MONITORING
TESTING
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)