Effects of ozone on symptoms and cardiopulmonary function in a flight attendant surrogate population

Journal Article · Sat Mar 01 00:00:00 EST 1980 · Aviat., Space Environ. Med.; (United States)

OSTI ID:5875712

Lategola, M T; Melton, C E; Higgins, E A

Two studies were conducted to ascertain the lowest ozone concentration threshold for statistically significant adverse effects on cardiopulmonary function and symptoms in male and female surrogates of the flight attendant population. Both studies simulated in-flight envionmental conditions at 1829 m mean sea level chamber altitude. The ozone exposures were 0.2 parts per million by volume for 4 h in the first study and 0.3 ppMv for 3 h in the second study. Each subject was similarly exposed to air only on another occasion. Treadmil exercise, equivalent to workloads of on-duty flight attendants, was performed at altitude. Cardiorespiratory measurements were made during ozone exposure, whereas spirometry and symptom assessments were made immediately before and after exposure. The ozone threshold for reversible adverse effects on symptoms and spirometry function was reached by a 3-h exposure to 0.3 ppMv. The data suggest a greater symptomatic sensitivity to ozone in females.

• Research Organization: Federal Aviation Administration, Oklahoma City, OK
• OSTI ID: 5875712
• Journal Information: Aviat., Space Environ. Med.; (United States), Vol. 51:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARDIOVASCULAR SYSTEM
SENSITIVITY
OZONE
BIOLOGICAL EFFECTS
RESPIRATORY SYSTEM
AIRCRAFT
ALTITUDE
ELECTROCARDIOGRAMS
HEART
OCCUPATIONAL SAFETY
PERSONNEL
PULSES
QUANTITY RATIO
BODY
DIAGRAMS
ORGANS
SAFETY
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)