Assessment of hand blood flow: A modified technique

Conference · Wed May 01 00:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:5875074

Kirsh, J C; Tepperman, P S

Radionuclide blood flow studies are frequently used in conjunction with static bone imaging of the hands to obtain valuable information regarding relative vascularity. This study was undertaken to demonstrate; a significant blood flow artefact with the conventional bolus injection technique (Tc-99m MDP) used in dynamic hand imaging, and a modified technique which virtually eliminates this artefact. The artefact is presumably due to reactive hyperemia induced by the tourniquet used to occlude venous return prior to injection. A modified technique was developed using intermittent injections of saline via a butterfly needle to maintain venous patency. This allows time for the reflex hyperemia to return to the basal state before injecting the radiopharmaceutical. Only 1 of 23 additional subject (4%) demonstrated significant artefactual asymmetry with the modified technique. A highly significant different (rho < .001) was observed between the two techniques. Additionally, there was no significant difference (rho = .50) between the observed pattern with the modified technique and the expected normal symmetrical pattern. Therefore, use of this technique will eliminate a potentially seriously misleading artefact.

• Research Organization: Mount Sinai Hospital, Toronto, Ontario
• OSTI ID: 5875074
• Report Number(s): CONF-850611-; TRN: 87-039234
• Journal Information: J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD FLOW
RADIOISOTOPE SCANNING
SCINTISCANNING
HANDS
RADIOPHARMACEUTICALS
BIOLOGICAL EFFECTS
DIAGNOSTIC USES
INTRAVENOUS INJECTION
PATIENTS
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DRUGS
HOURS LIVING RADIOISOTOPES
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIMBS
NUCLEI
ODD-EVEN NUCLEI
RADIOISOTOPES
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics