Cadmium content of human cancellous bone

Journal Article · Wed Sep 01 00:00:00 EDT 1982 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1982.10667581· OSTI ID:5856736

Knuuttila, M ^[1]; Lappalainen, R; Olkkonen, H; Lammi, S; Albava, E M

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1. Inst. of Dentistry, Kuopio, Finland

The cadmium content of human cancellous bone was related to age, sex, bone loss, physical properties, and elemental composition. Bone specimens from the anterior iliac crest were collected from 88 cadavers with a normal mineral status, and from 50 cadavers which had bone loss from chronic diseases and immobilization. The element concentrations were analyzed using atomic absorption spectrophotometry. Bone fluoride levels were determined with the ion specific electrode, the mineral density with the gamma ray attenuation method, and the compressive strength with a strain transducer. The data were analyzed using multiple linear regression analysis. The mean cadmium content of 0.22 +/- 0.16 ..mu..g/g dry weight (+/- SD) in the samples did not change with age and its content was slightly greater in males than in females. Furthermore, no statistically significant relationship was found in cadmium content to bone loss changes or to the calcium content of bone. The cadmium content had a high statistically significant positive correlation with the strontium and nickel content.

• OSTI ID: 5856736
• Journal Information: Arch. Environ. Health; (United States), Vol. 37:5
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
CONCENTRATION RATIO
FLUORIDES
COMPARATIVE EVALUATIONS
NICKEL
SKELETON
ABSORPTION SPECTROSCOPY
STRONTIUM
AGE GROUPS
AUTOPSY
BIOLOGICAL ACCUMULATION
CALCIUM
ION SELECTIVE ELECTRODE ANALYSIS
MAN
PHYSICAL PROPERTIES
REGRESSION ANALYSIS
SEX
SKELETAL DISEASES
TISSUE DISTRIBUTION
ALKALINE EARTH METALS
ANIMALS
BODY
CHEMICAL ANALYSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DISTRIBUTION
ELEMENTS
FLUORINE COMPOUNDS
HALIDES
HALOGEN COMPOUNDS
MAMMALS
MATHEMATICS
METALS
ORGANS
PRIMATES
SPECTROSCOPY
STATISTICS
TRANSITION ELEMENTS
VERTEBRATES
510200* - Environment
Terrestrial- Chemicals Monitoring & Transport- (-1989)
560306 - Chemicals Metabolism & Toxicology- Man- (-1987)