Skin blood flow during histamine flare using the clearance of epicutaneous applied Xenon-133 in diabetic and non-diabetic subjects

Journal Article · Fri Apr 01 00:00:00 EST 1983 · Angiology; (United States)

DOI:https://doi.org/10.1177/000331978303400401· OSTI ID:5855389

Hutchison, K J; Overton, T R; Biltek, K B; Nixon, R; Williams, H T

The increase in skin blood flow produced by both reactive hyperemia and histamine was examined in 8 normal, 8 diabetic and 3 cancer patients using the epicutaneous Xenon-133 clearance method. The histamine flare response in both diabetic and cancer groups was reduced compared to that in the normal group. There was no significant difference in the reactive hyperemia responses. It is concluded that the reduction in the histamine flare response is due to a defect in the sensory nerves mediating the axon reflex and not due to a change in the vascular response.

• Research Organization: Department of Physiology, Faculty of Medicine, University of Alberta, Edmonton, Canada
• OSTI ID: 5855389
• Journal Information: Angiology; (United States), Vol. 34:4
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
SKIN
BLOOD FLOW
ALLERGY
CARCINOMAS
DIABETES MELLITUS
HISTAMINE
PATHOLOGICAL CHANGES
PATIENTS
TRACER TECHNIQUES
XENON 133
AMINES
AZOLES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
ENDOCRINE DISEASES
EVEN-ODD NUCLEI
HETEROCYCLIC COMPOUNDS
IMIDAZOLES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
METABOLIC DISEASES
NEOPLASMS
NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RADIOISOTOPES
XENON ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics