Reverse-phase HPLC of benzylpropionitrile dithiocarbamate complexes for the determination of priority pollutant metals
A new dithiocarbamate, benzylpropionitrile dithiocarbamate (BPDTC), has been synthesized for use in metal analysis. The HPLC behavior of metal chelates of BPDTC has been investigated for the simultaneous determination of antimony, cadmium, chromium, copper, mercury, nickel, lead, selenium, thallium, and zinc, all of which are on the Environmental Protection Agency's list of priority pollutant metals. Metals are extracted into dichloromethane as BPDTC chelates, and then separated on a C-18 column. Cobalt is added as an internal standard. The effects of pH and of three organic modifiers (methanol, acetonitrile, tetrahydrofuran) of the mobile phase on retention time have been investigated. Addition of dichloromethane to the mobile phase increases solubility and chelate stability, and improves the separation of metal BPDTC complexes. BPDTC is added to the aqueous mobile phase to reduce on-column dissociation of the complexes. Detection limits at 260 nm are in the range of 0.1 to 3 ppb using a 1 liter sample.
- Research Organization:
- Akron Univ., OH (USA)
- OSTI ID:
- 5852718
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ANTIMONY
LIQUID COLUMN CHROMATOGRAPHY
CADMIUM
CHROMIUM
COPPER
LEAD
MERCURY
NICKEL
SELENIUM
THALLIUM
ZINC
ACETONITRILE
CARBAMATES
CHELATES
COBALT
COMPLEXES
EXTRACTION
METHANOL
PH VALUE
POLLUTANTS
POLYCYCLIC SULFUR HETEROCYCLES
SEPARATION PROCESSES
SOLUBILITY
TETRAHYDROFURAN
TIME DEPENDENCE
US EPA
ALCOHOLS
CARBONIC ACID DERIVATIVES
CARBOXYLIC ACID SALTS
CHROMATOGRAPHY
ELEMENTS
FURANS
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
METALS
NATIONAL ORGANIZATIONS
NITRILES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
SEMIMETALS
TRANSITION ELEMENTS
US ORGANIZATIONS
400102* - Chemical & Spectral Procedures