Taste aversion learning produced by combined treatment with subthreshold radiation and lithium chloride
These experiments were designed to determine whether treatment with two subthreshold doses of radiation or lithium chloride, either alone or in combination, could lead to taste aversion learning. The first experiment determined the thresholds for a radiation-induced taste aversion at 15-20 rad and for lithium chloride at 0.30-0.45 mEq/kg. In the second experiment it was shown that exposing rats to two doses of 15 rad separated by up to 3 hr produced a taste aversion. Treatment with two injections of lithium chloride (0.30 mEq/kg) did not produce a significant reduction in preference. Combined treatment with radiation and lithium chloride did produce a taste aversion when the two treatments were administered within 1 hr of each other. The results are discussed in terms of the implications of these findings for understanding the nature of the unconditioned stimuli leading to the acquisition of a conditioned taste aversion.
- Research Organization:
- Armed Forces Radiobiology Research Institute, Bethesda, MD
- OSTI ID:
- 5836603
- Journal Information:
- Pharmacol., Biochem. Behav.; (United States), Vol. 27:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
LITHIUM CHLORIDES
RADIOSENSITIVITY EFFECTS
TASTE BUDS
BIOLOGICAL RADIATION EFFECTS
LEARNING
RADIATION DOSES
RATS
SYNERGISM
ALKALI METAL COMPOUNDS
ANIMALS
BIOLOGICAL EFFECTS
BODY
CHLORIDES
CHLORINE COMPOUNDS
DOSES
HALIDES
HALOGEN COMPOUNDS
LITHIUM COMPOUNDS
LITHIUM HALIDES
MAMMALS
ORGANS
RADIATION EFFECTS
RODENTS
SENSE ORGANS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals