Vasa vasorum and angioplasty

Journal Article · Fri Jul 01 00:00:00 EDT 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.148.1.6222396· OSTI ID:5820793

Cragg, A H; Einzig, S; Rysavy, J A; Castaneda-Zuniga, W R; Borgwardt, B; Amplatz, K

Interruption of flow in the vasa vasorum may lead to medial neceosis and aneurysm formation. The purpose of this study was to determine whether angioplasty produces significant alterations in the morphology or blood flow of the vasa vasorum of the dilated artery. The morphology of the canine vasa vasorum was studied before and after angioplasty; in a separate experiment vessel wall blood flow (VWBF) in canine carotid arteries was measured after angioplasty to determine whether physiologic regulation of the blood flow was disrupted by arterial dilation. No morphologic changes could be demonstrated in the vasa vasorum of the dilated artery; however, VWBF was increased. Adenosine caused a paradoxical decrease in VWBF of the dilated arterial segment while causing increased VWBF in the thoracic aorta. Angioplasty appears to produce persistent hyperemia in the dilated arterial wall. A paradoxical response to adenosine suggests that vasa vasorum in the dilated arterial segment are maximally vasodilated. This may be due to mechanical disruption of vasomotor tone or to release of vasoactive substances.

• Research Organization: Univ. of Minnesota Hospitals, Minneapolis
• OSTI ID: 5820793
• Journal Information: Radiology; (United States), Vol. 148:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AORTA
BLOOD FLOW
DYNAMIC FUNCTION STUDIES
TRACER TECHNIQUES
BLOOD PRESSURE
CAROTID ARTERIES
CERIUM 141
DOGS
MICROSPHERES
MORPHOLOGY
NIOBIUM 96
STRONTIUM 85
SURGERY
ALKALINE EARTH ISOTOPES
ANIMALS
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CERIUM ISOTOPES
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MEDICINE
NIOBIUM ISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
STRONTIUM ISOTOPES
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics