Interstitial hyperthermia in combination with brachytherapy
Flexible coaxial cables were modified to serve as microwave antennas operating at a frequency of 915 MHz. These antennas were inserted ito nylon afterloading tubes that had been implanted in tumors using conventional interstitial implantation techniques for iridium-192 seed brachytherapy. The tumor volume was heated to 42 to 45/sup 0/C within 15 minutes and heating was continued for a total of 1 hour per treatment. Immediately following a conventional brachytherapy dose and removal of the iridium seeds the tumors were heated again in a second treatment. This interstitial technique for delivering local hyperthermia should be compatible with most brachytherapy methods. The technique has proved so far to be practical and without complications. Temperature distributions obtained in tissue phantoms and a patient are described.
- Research Organization:
- Dartmouth College, Hanover, NH
- OSTI ID:
- 5818457
- Journal Information:
- Radiology; (United States), Vol. 148:1
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AFTERLOADING
SIDE EFFECTS
HYPERTHERMIA
NEOPLASMS
ULCERS
RADIOINDUCTION
BIOLOGICAL RADIATION EFFECTS
IRIDIUM 192
MICROWAVE RADIATION
PATIENTS
PHANTOMS
SKIN
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
BODY TEMPERATURE
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
MOCKUP
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
STRUCTURAL MODELS
THERAPY
YEARS LIVING RADIOISOTOPES
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560151 - Radiation Effects on Animals- Man
560206 - Thermal Effects- Man- (-1987)