Genetic and physiological factors affecting repair and mutagenesis in yeast

Journal Article · Tue Jan 01 00:00:00 EST 1980 · Basic Life Sci.; (United States)

DOI:https://doi.org/10.1007/978-1-4684-3842-0_7· OSTI ID:5764748

Lemontt, J F

Current views of DNA repair and mutagenesis in the yeast Saccharomyces cerevisiae are discussed in the light of recent data and with emphasis on the isolation and characterization of genetically well-defined mutations that affect DNA metabolism in general. Various pathways of repair are described, particularly in relation to their involvement in mutagenic mechanisms. In addition to genetic control, certain physiological factors such as cell age, DNA replication, and the regulatory state of the mating-type locus are shown to also play a role in repair and mutagenesis.

• OSTI ID: 5764748
• Journal Information: Basic Life Sci.; (United States), Vol. 15
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL REPAIR
BIOCHEMICAL REACTION KINETICS
DNA
BIOLOGICAL PATHWAYS
DNA REPLICATION
GENETIC RADIATION EFFECTS
METABOLISM
MUTAGENESIS
PHYSIOLOGY
SACCHAROMYCES CEREVISIAE
ULTRAVIOLET RADIATION
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
ELECTROMAGNETIC RADIATION
FUNGI
GENETIC EFFECTS
KINETICS
MICROORGANISMS
NUCLEIC ACID REPLICATION
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PLANTS
RADIATION EFFECTS
RADIATIONS
REACTION KINETICS
RECOVERY
REPAIR
SACCHAROMYCES
YEASTS
550400* - Genetics
560112 - Radiation Effects on Biochemicals- In Microorganisms- (-1987)