Relationship of blood lead to blood pressure in a longitudinal study of working men

Journal Article · Thu May 01 00:00:00 EDT 1986 · Am. J. Epidemiol.; (United States)

OSTI ID:5735755

Weiss, S T; Munoz, A; Stein, A; Sparrow, D; Speizer, F E

The relationship of lead exposure to blood pressure has been examined in a longitudinal study of a cohort of 89 Boston, Massachusetts, policemen. At the baseline examination, subjects had a blood lead determination and three consecutive blood pressure measurements. Triplicate blood pressure measurements were also taken at years 3, 4, and 5. Multivariate analysis revealed that, after correction for previous systolic blood pressure, body mass index, age, and smoking, a high level of blood lead was a significant predictor of subsequent elevation of systolic pressure. Bootstrap simulations of these models provided supporting evidence for the observed associations. These data suggest that lead exposure can significantly affect systolic pressure.

• Research Organization: Charles A. Dana Research Institute, Boston, MA
• OSTI ID: 5735755
• Journal Information: Am. J. Epidemiol.; (United States), Vol. 5
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
LEAD
HEALTH HAZARDS
BIOLOGICAL INDICATORS
BLOOD PRESSURE
MASSACHUSETTS
MULTIVARIATE ANALYSIS
OCCUPATIONAL EXPOSURE
PERSONNEL
TOBACCO SMOKES
AEROSOLS
COLLOIDS
DISPERSIONS
ELEMENTS
FEDERAL REGION I
HAZARDS
MATHEMATICS
METALS
NORTH AMERICA
RESIDUES
SMOKES
SOLS
STATISTICS
USA
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)