In vivo incorporation of labeled fatty acids in rat liver lipids after oral administration
Striking differences were found in the compartmentalization of fatty acids into liver lipid fractions. The saturated fatty acids--lauric, myristic, palmitic and stearic--were incorporated into phosphoglycerides at faster rates with increasing chain lengths, while triglyceride incorporation was almost uniform. The degree of incorporation of the unsaturated fatty acids into phosphoglycerides (structural) compared to triglyceride (storage and energy) was the converse of their oxidation rates. The incorporation of oleic, linoleic and alpha-linolenic acids was mainly into triglyceride, whereas dihomo-gamma-linolenic acid and arachidonic acid were preferentially incorporated into phosphoglycerides. The data suggest that distribution of each fatty acid is different depending on its destination for structural or energy function.
- Research Organization:
- Institute of Zoology, London, England
- OSTI ID:
- 5726261
- Journal Information:
- Lipids; (United States), Vol. 22:8
- Country of Publication:
- United States
- Language:
- English
Similar Records
The Use of Raman Spectroscopy and Methods of Quantum Chemistry for Assessing the Relative Concentration of Triglycerides of Oleic and Linoleic Acids in a Mixture of Olive Oil and Sunflower Seed Oil
Novel Bioplastics and biocomposites from Vegetable Oils
Related Subjects
CARBOXYLIC ACIDS
METABOLISM
PHOSPHOLIPIDS
BIOSYNTHESIS
IN VIVO
LABELLED COMPOUNDS
LIVER
ORAL ADMINISTRATION
RADIOISOTOPES
RATS
TISSUE DISTRIBUTION
TRACER TECHNIQUES
TRIGLYCERIDES
ANIMALS
BODY
DIGESTIVE SYSTEM
DISTRIBUTION
ESTERS
GLANDS
ISOTOPE APPLICATIONS
ISOTOPES
LIPIDS
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
RODENTS
SYNTHESIS
VERTEBRATES
550501* - Metabolism- Tracer Techniques