Action of dextran-modified hyaluronidase in experimental silicosis
Journal Article
·
· Bull. Exp. Biol. Med. (Engl. Transl.); (United States)
The authors study the effect of hyaluronidase stabilized by covalent addition to dextran, modified by partial oxidation, on the development of the pneumofibrosis in silicosis. Rats were used in the investigations. Of the two preparations studied with stabilized hyaluronidase action, that stabilized by covalent addition of lidase to aldehyde-dextran proved to be the more effective.
- Research Organization:
- Research Institute of Work Hygiene and Occupational Diseases, Moscow, USSR
- OSTI ID:
- 5718924
- Journal Information:
- Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Vol. 103:2; Other Information: Translated from Byulleten' Ehksperimental'noj Biologii i Meditsiny; 103: No. 2, 221-223(Feb 1987)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
DEXTRAN
BIOLOGICAL EFFECTS
HYALURONIDASE
ENZYME ACTIVITY
PNEUMOCONIOSES
THERAPY
ADDITIVES
FIBROSIS
INDUSTRIAL WASTES
INHALATION
INTRAPERITONEAL INJECTION
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
ORAL ADMINISTRATION
RATS
SILICON COMPOUNDS
ANIMALS
BLOOD SUBSTITUTES
CARBOHYDRATES
DISEASES
DRUGS
ENZYMES
GLYCOSYL HYDROLASES
HEMATOLOGIC AGENTS
HYDROLASES
INJECTION
INTAKE
MAMMALS
O-GLYCOSYL HYDROLASES
ORGANIC COMPOUNDS
PATHOLOGICAL CHANGES
POLYSACCHARIDES
RESPIRATORY SYSTEM DISEASES
RODENTS
SACCHARIDES
VERTEBRATES
WASTES
560300* - Chemicals Metabolism & Toxicology
550600 - Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
DEXTRAN
BIOLOGICAL EFFECTS
HYALURONIDASE
ENZYME ACTIVITY
PNEUMOCONIOSES
THERAPY
ADDITIVES
FIBROSIS
INDUSTRIAL WASTES
INHALATION
INTRAPERITONEAL INJECTION
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
ORAL ADMINISTRATION
RATS
SILICON COMPOUNDS
ANIMALS
BLOOD SUBSTITUTES
CARBOHYDRATES
DISEASES
DRUGS
ENZYMES
GLYCOSYL HYDROLASES
HEMATOLOGIC AGENTS
HYDROLASES
INJECTION
INTAKE
MAMMALS
O-GLYCOSYL HYDROLASES
ORGANIC COMPOUNDS
PATHOLOGICAL CHANGES
POLYSACCHARIDES
RESPIRATORY SYSTEM DISEASES
RODENTS
SACCHARIDES
VERTEBRATES
WASTES
560300* - Chemicals Metabolism & Toxicology
550600 - Medicine