Utility of three-phase skeletal scintigraphy in suspected osteomyelitis: concise communication
Three-phase skeletal scintigraphy, consisting of a radionuclide angiogram, an immediate postinjection ''blood-pool'' image, and 2-3 hr delayed images, was performed on 98 patients with suspected osteomyelitis. This procedure was evaluated by first interpreting only the delayed images, next the combination of ''blood-pool'' and delayed images, and finally the three-phase study. There was no change in the sensitivity (12/13 = 0.92) for detecting osteomyelitis, but the false-positive rate for osteomyelitis decreased from 0.25 (21/85) to 0.06 (5/85). In 21 of 64 patients (33%) with abnormal studies, the ''blood-pool'' image and/or the radionuclide angiogram led to a more accurate scintigraphic diagnosis. In 12 patients (19%) the ''blood-pool'' alone was enough to achieve the correct final diagnosis and was used most often to identify noninfectious disease. In 9 patients (14%) the radionuclide angiogram was required for an accurate interpretation and was considered essential most often in cases of soft-tissue infection. Both radionuclide angiography and ''blood-pool'' imaging appear to augment the specificity of skeletal scintigraphy in patients with suspected osteomyelitis.
- Research Organization:
- Johns Hopkins Medical Inst. Baltimore, MD
- OSTI ID:
- 5714542
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 22:11
- Country of Publication:
- United States
- Language:
- English
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OSTEOMYELITIS
DIAGNOSIS
SKELETON
SCINTISCANNING
BIOMEDICAL RADIOGRAPHY
ISOMERIC NUCLEI
PATIENTS
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
SKELETAL DISEASES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics