Late nonstochastic changes in pig skin after. beta. irradiation

Journal Article · Fri Mar 01 00:00:00 EST 1985 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576508· OSTI ID:5707425

Peel, D M; Hopewell, J W; Wells, J; Charles, M W

Late radiation-induced changes in pig skin have been assessed following irradiation with ..beta..-rays from a 22.5- or 15-mm-diameter /sup 90/Sr//sup 90/Y source and a 19- or 9-mm-diameter /sup 170/Tm source. Late damage, in terms of dermal atrophy, was assessed 2 years after irradiation from measurements of dermal thickness of 40-50% of the control value, occurred at a dose of approx. 40 Gy from the 22.5-mm source and approx. 75 Gy from the 15-mm source. In the case of /sup 170/Tm the 19- and 9-mm sources produced similar degrees of atrophy at equal doses. Maximum atrophy occurred at approx. 70 Gy, when the dermis was approx. 70% of the thickness of normal skin. Significant late tissue atrophy was seen at doses, from both types of radiation, which only produced minimal erythema in the early reaction. Such late reactions need to be taken into account when revised radiological protection criteria are proposed for skin.

• Research Organization: Research Institute Univ. of Oxford, England
• OSTI ID: 5707425
• Journal Information: Radiat. Res.; (United States), Vol. 101:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ATROPHY
RADIOINDUCTION
SKIN
DELAYED RADIATION EFFECTS
BETA PARTICLES
STRONTIUM 90
SWINE
THULIUM 170
YTTRIUM 90
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CHARGED PARTICLES
DAYS LIVING RADIOISOTOPES
DOMESTIC ANIMALS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-EVEN NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
STRONTIUM ISOTOPES
THULIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
YTTRIUM ISOTOPES
560152* - Radiation Effects on Animals- Animals