Immunization of Baboons with Schistosoma mansoni Cercariae attenuated by gamma irradiation
Journal Article
·
· Science (Washington, D.C.); (United States)
Studies on the efficacy of a vaccine against schistosomiasis in young baboons (Papio anubis) disclosed that immunization with Schistosoma mansoni cercariae attenuated by gamma irradiation induced significant protection against subsequent infection with normal, viable S. mansoni cercariae. Such immunization resulted in reduced worm burdens (70 percent) and egg excretion rates (82 percent). These results support immunization as a potential method for schistosomiasis control.
- OSTI ID:
- 5704278
- Journal Information:
- Science (Washington, D.C.); (United States), Vol. 212:4502
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
SCHISTOSOMA
BIOLOGICAL RADIATION EFFECTS
SCHISTOSOMIASIS
VACCINES
APES
GAMMA RADIATION
IMMUNITY
INFECTIVITY
INOCULATION
ANIMALS
BIOLOGICAL EFFECTS
DISEASES
ELECTROMAGNETIC RADIATION
HELMINTHS
INFECTIOUS DISEASES
IONIZING RADIATIONS
MAMMALS
PARASITIC DISEASES
PLATYHELMINTHS
PRIMATES
RADIATION EFFECTS
RADIATIONS
TREMATODES
VERTEBRATES
560134* - Radiation Effects on Microorganisms- Vaccine Preparation & Other Applications- (-1987)
SCHISTOSOMA
BIOLOGICAL RADIATION EFFECTS
SCHISTOSOMIASIS
VACCINES
APES
GAMMA RADIATION
IMMUNITY
INFECTIVITY
INOCULATION
ANIMALS
BIOLOGICAL EFFECTS
DISEASES
ELECTROMAGNETIC RADIATION
HELMINTHS
INFECTIOUS DISEASES
IONIZING RADIATIONS
MAMMALS
PARASITIC DISEASES
PLATYHELMINTHS
PRIMATES
RADIATION EFFECTS
RADIATIONS
TREMATODES
VERTEBRATES
560134* - Radiation Effects on Microorganisms- Vaccine Preparation & Other Applications- (-1987)